成人大片

Researchers from the 成人大片 have found that throat cancers caused by human papilloma virus (HPV), a common sexually transmitted disease, are 15 times more prevalent in Indigenous Australians than young non-Indigenous Australians, and five times the prevalence reported in a systematic review involving the US, Brazil, Mexico and Finland.

The initial findings have led to a continuation of the world-leading study for the next five years thanks to $3.1 million in funding from the National Health and Medical Research Council.

The ultimate goal of the research is to detect early signs of HPV-related oropharyngeal cancer before it becomes fatal.

HPV is normally associated with cervical cancer, but can spread to the throat, head and neck via oral sexual activities, and is increasing at a rapid rate globally.

Director of the 成人大片鈥檚 Australian Research Centre for Population Oral Health (ARCPOH), Professor Lisa Jamieson, said extending the study would allow a deep dive of the critical knowledge they had already learnt.

鈥淲e found that the prevalence of oral HPV was about 15 times higher in the Indigenous population than the general population,鈥� Professor Jamieson said.

鈥淭here鈥檚 two types of oral HPV, types 16 and 18, that are linked to oropharyngeal cancer, out of the more than 250 types overall.

鈥淪ixteen and 18 have the strongest carcinogenic potential 鈥� type 16 has an almost 100 per cent risk of getting cancer 鈥� so it鈥檚 important we understand how prevalent this disease is in Indigenous communities.

鈥淲e鈥檒l be doing thorough clinical examinations, which includes a full dental check of the teeth, the tongue, the backs of the throat, and taking blood samples to test for early stages of cancer.鈥�

鈥淟ike all cancers, if this can be detected early, it not only means less deaths, but also much improved quality of life for people who survive due to the need for less extensive surgery and other cancer treatment."Dean and Head of School, Professor Richard Logan

More than 1,000 Indigenous people from across South Australia 鈥� including Adelaide, Mount Gambier, Coober Pedy, Ceduna, Whyalla, Port Lincoln, Port Pirie and the Riverland 鈥� were recruited for the study, which started in 2019.

Director of the University鈥檚 Indigenous Oral Health Unit (IOHU), Ms Joanne Hedges, is the chief investigator on the study.

The Yamatji woman has worked closely with the Indigenous communities to understand their concerns about how to deal with the disease.

鈥淧articipants wanted to be part of this HPV project because they wanted to be part of change,鈥� Ms Hedges said.

鈥淭he theme coming out was, 鈥業 had a family member pass away with this throat sickness, and I don鈥檛 want to happen to any other Nunga in my community or my family鈥�.

鈥淭here was a real strength of participation.鈥�

Dean and Head of School, Professor Richard Logan, said this project is a fantastic example of researchers and the community working together, and another reason why the Adelaide Dental School, which includes ARCPOH and IOHU, is the highest-ranked dental school in the country.

鈥淟ike all cancers, if this can be detected early, it not only means less deaths, but also much improved quality of life for people who survive due to the need for less extensive surgery and other cancer treatment,鈥� Professor Logan said.

The investigator team also includes Murthy Mittinty (成人大片), Gail Garvey (University of Queensland), Lisa Whop (Australian National University), Karen Canfell (University of Sydney), Zell Dodd (Yadu Health Aboriginal Corporation), Priscilla Larkins (Umoona Tjutagku Health Serivce), Annika Antonsson (QIMR) and Megan Smith (University of Sydney).

The findings of the research have been published in medical journal .