Dinosaur relative鈥檚 genome linked to mammals
Scientists from the 成人大片 and South Australian Museum have collaborated with Otago University, New Zealand and a global team to sequence the genome of the tuatara 鈥 a rare reptile whose ancestors once roamed the earth with dinosaurs.
The findings on this remarkable living, single species reptile, which originated in 迟丑别听Triassic听period around 250 million years ago and is only found in New Zealand, have been published in .
Professor David Adelson鈥檚 lab of the 成人大片鈥檚 Department of Molecular and Biomedical Science and Dr Terry Bertozzi of the South Australian Museum carried out key analysis of the tuatara genome that revealed an unusual architecture, half-way between mammal and reptile.听
鈥淭he tuatara is the last surviving species of a reptile group that roamed the earth with the dinosaurs and remarkably, its genome shares features with those of mammals such as the platypus and echidna."Professor David Adelson, the 成人大片.
鈥淭he tuatara is the last surviving species of a reptile group that roamed the earth with the dinosaurs and remarkably, its genome shares features with those of mammals such as the platypus and echidna,鈥 said Professor Adelson.
The key contribution of Professor Adelson鈥檚 lab and Dr Bertozzi was to demonstrate that some sequences of DNA that move or jump location, referred to as 鈥榡umping genes鈥, found in the tuatara are most similar to those found in platypus while others are more similar to those in lizards.
鈥淭he tuatara genome contained about 4% jumping genes that are common in reptiles, about 10% common in monotremes (platypus and echidna) and less than 1% common in placental mammals such as humans,鈥 said Professor Adelson.
鈥淭his was a highly unusual observation and indicated that the tuatara genome is an odd combination of both mammalian and reptilian components.鈥
鈥淭he unusual sharing of both monotreme and reptile-like repetitive elements is a clear indication of shared ancestry albeit a long time ago,鈥 said Dr Bertozzi.
With no close relatives, the position of tuatara on the tree of life has long been contentious. The research places tuatara firmly in the branch shared with lizards and snakes, but they appear to have split off and been their own species for around 250 million years 鈥 an enormous amount of time given primates only originated around 65 million years ago, and hominids, from which humans descend, originated approximately six million years ago.
鈥淚t has been a privilege to be part of this project, which has been a true, historic collaboration with local iwi (M膩ori indigenous tribe) Ng膩tiwai. While this is largely fundamental science, I expect it to yield new ways of thinking about our own genome structure that may have relevance to our health,鈥 said Professor Adelson.
Media Contacts:
Professor David Adelson
Department of Molecular and Biomedical Science
The 成人大片
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Email: david.adelson@adelaide.edu.au
Kelly Brown
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External Relations
The 成人大片
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Ashleigh听Glynn
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South Australian Museum
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Email: ashleigh.glynn@samuseum.sa.gov.au