World鈥檚 smallest imaging device has heart disease in focus

Ultrathin 3D printed endoscope imaging an artery_credit_ Simon Thiele and Jiawen Li

Ultrathin 3D printed endoscope imaging an artery - photo by Simon Thiele and Jiawen Li.

A team of researchers led by the 成人大片 and University of Stuttgart has used 3D micro-printing to develop the world鈥檚 smallest, flexible scope for looking inside blood vessels.

The camera-like imaging device can be inserted into blood vessels to provide high quality 3D images to help scientists better understand the causes of heart attack and heart disease progression, and could lead to improved treatment and prevention.



In a study published in the journal , a multidisciplinary team of researchers and clinicians was able to 3D print a tiny lens on to the end of an optical fibre, the thickness of a human hair.

The imaging device is so small that researchers were able to scan inside the blood vessels of mice.

Dr Jiawen Li, co-author and Heart Foundation Postdoctoral Fellow at the Institute for Photonics and Advanced Sensing, 成人大片, says in Australia cardiovascular disease kills one person every 19 minutes.

鈥淎 major factor in heart disease is the plaques, made up of fats, cholesterol and other substances that build up in the vessel walls,鈥 Dr Li said.

鈥淧reclinical and clinical diagnostics increasingly rely on visualising the structure of the blood vessels to better understand the disease.

鈥淢iniaturised endoscopes, which act like tiny cameras, allow doctors to see how these plaques form and explore new ways to treat them,鈥 she said.

Dr Simon Thiele, Group Leader, Optical Design and Simulation at the University of Stuttgart, was responsible for fabricating the tiny lens.

鈥淯ntil now, we couldn鈥檛 make high quality endoscopes this small,鈥 Dr Thiele said.

鈥淯sing 3D micro-printing, we are able to print complicated lenses that are too small to see with the naked eye.

鈥淭he entire endoscope, with a protective plastic casing, is less than half a millimetre across,鈥 he said.

Dr Li explains: 鈥淚t鈥檚 exciting to work on a project where we take these innovations and build them into something so useful.

鈥淚t鈥檚 amazing what we can do when we put engineers and medical clinicians together,鈥 said Dr Li.

The research collaboration also included researchers from The South Australian Health and Medical Research Institute, The Royal Adelaide Hospital and Monash University.

Tagged in heart disease, heart attack, endoscope, 3D printing