MICRO 3007 - Infection & Immunity A (Theory) III

North Terrace Campus - Semester 1 - 2025

This advanced course examines the molecular basis of interactions of microbial pathogens with their environment and various hosts, especially those which infect humans. Bacterial pathogens of global and medical significance that will be highlighted in detail include: Streptococcus pneumonia, Salmonella sp., Shigella sp., Staphylococcus sp., Mycobacterium; and Neisseria sp. Particular emphasis is given to the use of molecular biological approaches for study of bacterial infectious disease pathogenesis, and biotechnological applications, including vaccine development will also be highlighted. Topics to be explored include: bacterial pathogens - global significance of infectious disease; principal approaches for investigating host-pathogen interactions; the role of innate immunity and defence mechanisms; the microbiota; virulence factors which promote colonisation and damage to the host; cell surface polysaccharides and proteins; role of antigenic and phase variation in virulence and disease; gene regulation, especially in relation to expression of virulence factors; stress responses; invasion and intracellular survival and multiplication; resistance and avoidance of innate host defences; bacterial toxins; antibiotic resistance; vaccines and therapeutic interventions; genomic approaches to analysis of virulence; parasites including malaria and viruses. The lecture program is complemented by tutorials, which extend skills in exploring and critically assessing the scientific literature, and practicals which develop advanced experimental skills for the study of bacterial pathogenic mechanisms.

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Course Details

Course Code	MICRO 3007
Course	Infection & Immunity A (Theory) III
Coordinating Unit	Molec & Biomedical Science
Term	Semester 1
Level	Undergraduate
Location/s	North Terrace Campus
Units	3
Contact	3 x 1 hour lectures per week, 1 x 2 hour tutorials/workshops per fortnight
Available for Study Abroad and Exchange	Y
Prerequisites	MICRO 2500 or MICRO 2504; or equivalent
Incompatible	MICRO 3102, MICRO 3000
Assessment	Tutorials, problem solving questions, final exam

Course Staff

Course Coordinator: Professor Michael Beard

Course Timetable

The full timetable of all activities for this course can be accessed from .

Learning Outcomes

Course Learning Outcomes

No information currently available.

University Graduate Attributes

No information currently available.
Learning & Teaching Activities

Learning & Teaching Modes

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Workload

No information currently available.

Learning Activities Summary

Week Type of learning activity Topic

1 Lectures Bacteria-host interactions and innate defences

2 Lectures Bacteria-host interactions and innate defences;
Gut pathogens; Intracellular bacterial pathogens

Tutorial Critical thinking and analysis of primary research papers related to lecture material

3 Lectures Intracellular bacterial pathogens
Bacteria and subversion of host cell biology

4 Lectures Cell surface polysaccharides
Gene regulation and the host environment

Tutorial Critical thinking and analysis of primary research papers related to lecture material

5 Lectures Antibiotics

6 Lectures Vaccines
Tutorial Critical thinking and analysis of primary research papers related to lecture material

7 Lecture Microbiota, Streptococus

8 Lectures Stress responses

Tutorial Critical thinking and analysis of primary research papers related to lecture material, including problem solving questions workshop

9 Lectures Mucosal, skin, and respiratory tract pathogens

10 Lecture Respiratory tract pathogens; Gene expression in vivo

Tutorial Critical thinking and analysis of primary research papers related to lecture material, including problem solving questions workshop

11 Lecture Parasites: Viruses

12 Lecture Parasites: Viruses and Malaria

13 Problem solving questions assignment

The University's policy on Assessment for Coursework Programs is based on the following four principles:

Assessment must encourage and reinforce learning.
Assessment must enable robust and fair judgements about student performance.
Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
Assessment must maintain academic standards.

Assessment Summary

No information currently available.

Assessment Detail

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Submission

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Course Grading

Grades for your performance in this course will be awarded in accordance with the following scheme:

M10 (Coursework Mark Scheme)
Grade	Mark	Description
FNS		Fail No Submission
F	1-49	Fail
P	50-64	Pass
C	65-74	Credit
D	75-84	Distinction
HD	85-100	High Distinction
CN		Continuing
NFE		No Formal Examination
RP		Result Pending

Further details of the grades/results can be obtained from Examinations.

Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.

Final results for this course will be made available through .

Student Feedback

The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.

SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.
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Authorised by:	Deputy Vice-Chancellor and Vice-President (Academic)
Maintained by:	Course Outlines Administrator

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