成人大片

Name	Role	Building/Room	Email
Dr Beth Loveys	Course Coordinator	G26, Charles Hawker Building, Waite Campus	beth.loveys@adelaide.edu.au
Assoc. Prof. Chris Ford	Lecturer	WIC 4.43, Waite Campus	christopher.ford@adelaide.edu.au

1	Describe the role of thermodynamics in the determination of biochemical reactivity and differentiate between the kinetic and thermodynamic factors influencing biochemical reactions.
2	Explain how protein structure and function is derived from the constituent amino acids, and compare the features of structural and globular proteins.
3	Describe the basic principles governing the rate of enzyme catalysed reactions and the forms of inhibition of enzyme-catalysed reactions.
4	Describe the major pathways of carbohydrate and lipid metabolism and demonstrate how energy is stored and released through them.
5	Demonstrate familiarity and competance with the practica skills and techniques used in biochemisal research and analysis. This will include experimental planning, the preparation of reagents and use of basic instrumentation (spectrophotmeters, centrifuges, chromatographic apparatus etc, the collection of biochemical data and its presentation, and most importantly the analysis and interpretation of the outcomes of biochemical investigations.

There is no required textbook for this course.

The recommended text for this course is Tymoczko, Stryer and Berg (2015) Biochemistry A Short Course 3^rd Edition. 

Advanced treatment of topics covered during the course will be found in many of the major undergraduate biochemical textbooks. Students seeking further details and greater coverage of topics than are provided by the recommended text are encouraged to consider supplementing their study using one of these. Other good biochemistry texts include:

• Nelson and Cox (2012) Lehninger’s Principles of Biochemistry 6^th Edition
• Berg, Tymoczko and Stryer (2006) Biochemistry 6^th Edition
• Mathews, Van Holde and Ahern (2000) Biochemistry.

A limited number of copies of some of these texts will be held on Reserve in the Waite library.

The publisher (WH Freeman and Company) offers a range of eBook options for access to the texts by Tymoczko et al., Berg et al. and Nelson & Cox. Some of these may be available for use by Australian students

A shorter biochemistry ebook suitable for Kindle readers or the Kindle App on iPads etc, Instant Notes in Biochemistry 2^nd Edition, by David Hames, is available for purchase or short-term rental from the Kindle store. While this book does not cover topics in the depth provided by any of the major textbooks mentioned above, it nonetheless provides a useful background to all of the topics covered in the course.

 A reading list of references relevant to topics covered in the course, which in many instances will provide the research context around these topics, is provided and can be accessed from MyUni. Individual articles contained on the reading list may be downloaded for private study. From time to time during the course, lecturing staff, tutors etc may suggest that you read additional scientific papers. These will be made available for online reading and download via MyUni; full details will be given as appropriate.

MyUni: Teaching materials and course documentation will be posted on the MyUni website ().

Course administration is accomplished using MyUni: activities will include email, Announcements, lecture handouts and recordings, an online reading list and links to past examinations. Coursework assignments may be submitted through Turnitin as directed. Coursework marks will be made available through the Gradebook. Assessment in the form of online quizzes will be offered during the semester as a part of the Formative Assessment component.  All materials will be released at the relevant time during the semester.

Online activities for use before practical classes will be delivered using MyUni.

Lectures:

There are two lectures (each of 1 hour duration) per week; the first hour of lectures may be used to revise the previous week's lecture material.

Lecture notes may be posted to MyUni a few days in advance of the respective lecture and will not generally be provided to students in hard copy. Every attempt will be made to record lectures, and to make them available for streaming and download from MyUni.

A student enrolled in a 3 unit course, such as this, should expect to spend, on average 12 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., pre-class preparation, post-class assessments, reading and revision).

Week	Lecture	Practical	Tutorial
1	Introduction and proteins	Nitrite determination	Calculations
2	Proteins and enzymes	Nitrite determination	Calculations
3	Calculations test and enzymes	Enzyme kinetics	Enzymes
4	Lipids	Enzyme kinetics	Enzymes
5	Libids and haemoglobin	Ion exchange chromatography	Lipids
6	Carbohydrates	Ion exchange chromatography	Lipids
7	Carbohydrates and metabolism	Glucose extraction	Carbohydrates
8	Glycolysis	Glucose extraction	Carbohydrates
9	Glycolysis and beta oxidation	Starch extraction	Metabolism
10	Oxidative phosporylation	Starch extraction	Metabolism
11	Gluconeogenesis	Sports physiology TBL	Sports physiology TBL
12	Amino acids and urea cycle	Revision	Revision

Lecture 1 (10-11) Lecture 2 (11-12) Week1 Course introduction Proteins  Week 2 Revision proteins  Enzymes Week 3 Calculations test  Revision Enzymes Week 4 Lipids Lipids Week 5 Lipids revision Hb and Myoglobin  Week 6 Carbohydrates Biofuels Week 7 Carbohydrates revision  Metabolism  Week 8 Glycolysis  Low alcohol wine Week 9 Metabolism and glycolysis revision  Beta oxidation  Week 10 Oxidative phosphorylation Oxidative phosphorylation Week 11 Pathways revision Gluconeogenesis/regulation Week 12 Amino acids/urea Gluconeogenesis revision 

PRACTICAL SESSION CODE OF CONDUCT All students must follow these rules in practical exercises:

• Our students are from many countries, and speak in many different languages. The language of tuition and assessment of all courses at the 成人大片 is English. Our teaching and demonstrating staff work exclusively in English and it is vital therefore that all discussion and communication between students in all class situations is in English ONLY. This is of particular importance with respect to laboratory classes, in which the Health, Safety and Wellbeing of all participants are at all times the most important consideration. It is expected that ALL students will be respectful and understanding of the diversity of language skills possessed by class members, and where appropriate will provide explanation and guidance to peers.
• No eating, drinking, application of makeup, etc in laboratories; no water bottles or items of food or drink may be visible in laboratories; mobile phone calls to be taken and made outside the laboratory only.
• Closed shoes must be worn at all times in all practical exercises, wherever they are held.
• Lab coats and other personal protective equipment must be worn at all times in laboratories or other areas whenever students are instructed to wear them; these should be removed when leaving the laboratory.
• Bags, coats, etc. that are brought into a lab must be placed under the bench to avoid causing obstructions.
• All containers used during a practical session must be labelled, including water and other common non-toxic substances.
• Report all accidents, personal or involving experimental materials, to the person in charge.
• Playing around in a laboratory and many other work areas is dangerous; participants in improper behaviour will be asked to leave.
• Students must dispose of materials as directed.
• Students must wash their hands upon departing the labs and other work areas.
• Students must clean and tidy their bench and/or work area before departure; benches and/or work areas will be inspected at the end of each practical session.
• Students not complying with the rules will not receive credit for the practical session in which the breach occurred.

Due to the current COVID-19 situation modified arrangements have been made to assessments to facilitate remote learning and teaching.

No elements of the course have a formal exemption from the requirements of the Assessment for Coursework Programs Policy.

Assessment task	Task type	Due	Weighting	Learning Outcome
Practical report - starch extraction	Summative/Formative	Week 11 or 12	10%	4,5
Practical skills and biochemical calculations - Online test	Summative/Formative	Week 3	7.5%	5
Laboratory notebook	Summative/Formative	Week 7	5%	5
Online quizzes	Summative/Formative	Ongoing during semester	7.5%	1-4
Tutorial Question Answer Sheets	Summative/Formative	Weeks 1 or 2, 3 or 4, 5 or 6 and 9 or 10	5%	1-4
Big Bang Bichem	Summative/Formative	Weeks 11 and 12	15%	4,5
Exam	Summative		50%	1-4

Coursework formative and summative assessment - details:

Formative and summative assessment for the course will be covered by the following items:

Practical class reports, laboratory book presentation and online test (22.5%):
a. There will be practical classes conducted  over the course of the semester. Each of these will incorporate assessment of work submitted as laboratory notebook or a formal report write-up (10%).
All submitted work will be returned with feedback within 2 weeks of submission.

b. You will be supplied with a laboratory notebook and detailed instructions on its use. The notebooks will be checked at intervals during the course and assessed in weeks 12 or 13 (5%). The marks awarded for the laboratory notebook will be added to those for the practical assessments.

c. An online test (7.5%) will be held during the first lecture period in week 3. The test will comprise questions covering the biochemical calculations and basic practical skills encountered in weeks 1 and 2.

Online quizzes (7.5%)
During the semester, weekly online quizzes will be set from within MyUni/Assessments. Each quiz will contain between 5-10 questions, which will comprise a number of formats including but not limited to multiple choice, missing words, ordering
and calculations. Quizzes will normally be available immediately after the lecture until midnight (to test recall) and then again 24 hours after the lecture (to test understanding and improve retention)

Thequizzes are intended to provide each student with a brief assessment of their knowledge of topics covered in recent and past lectures and tutorials. Each quiz may be attempted only once; you will receive full answers upon completion of the quiz.

Tutorial assessments (5%):
Tutorial classes will be held in weeks 1 or 2, 3 or 4, 5 or 6, 7 or 8, 9 or 10. You will attend tutorials in the weeks when you are not scheduled for practical classes. The tutorial classes will comprise two one-hour sessions. In the first of these ('reinforcement tutorials') you will be required to provide answers to questions, provided through MyUni a week before your class, based on material covered in the relevant earlier lectures. Full details will be provided in week 1 or 2 as appropriate. The second session ('extension tutorials') will seek to guide you to an in-depth understanding of the topic, through a series of short class-based discussion questions designed to extend the knowledge gained in the lectures.

Big Bang Biochem (15%):
Students work online in pairs, they are allocated a topic and present via zoom in 3 min thesis style.
 
Summative (examination-based) Assessment - details:

Final Exam (50%):
The final examination in the Semester 1 exam period will consist of a 3-hour paper, containing questions derived from lectures delivered in weeks1-12 and the associated tutorials. All questions must be answered.

Late submission of assessments

If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days or more late without an approved extension can only receive a maximum of 50% of the mark.