PHARM 2100 - Pharmacology IIA - Drugs and Health

North Terrace Campus - Semester 1 - 2015

The course introduces students to basic pharmacological concepts and principles needed to understand the effects of drugs in humans. Students will gain an appreciation for how drugs interact with cellular target molecules, as well as for the cellular and physiological responses resulting from such interactions. These concepts will be illustrated by examining major drug classes and their use in the treatment of major human diseases, including drugs that influence the central nervous system.

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Course Details

Course Code	PHARM 2100
Course	Pharmacology IIA - Drugs and Health
Coordinating Unit	Clinical and Experimental Pharmacology
Term	Semester 1
Level	Undergraduate
Location/s	North Terrace Campus
Units	3
Contact	Up to 4 hours per week
Available for Study Abroad and Exchange	Y
Prerequisites	6 units of level I Biology courses: BIOLOGY 1101 & BIOLOGY 1201 or ANAT SC 1102 & ANAT SC 1103 (or equivalent with approval of Head of Discipline)
Assessment	Exam on lecture material, assessment test, online assignments

Course Staff

Course Coordinator: Dr Abdallah Salem

Course Coordinator: Dr Abdallah Salem
Phone: +61 8 8313 4321
Email: abdallah.salem@adelaide.edu.au
Location: Room N506, Level 5, Medical School North

Course Timetable

The full timetable of all activities for this course can be accessed from .

Course Learning Outcomes

1	To demonstrate knowledge of basic concepts in modern pharmacology, including familiarity with drug and receptor interactions, basic pharmacokinetic concepts.
2	To explain how drug actions can be exploited in the treatment of important human diseases, including mental disorders, inflammatory conditions, infectious disease, cancer and asthma.
3	To develop skills in the analysis of drug-related research data, including drug dosing calculations, evaluation of differences in potency among drugs; statistical data analysis.
4	To describe the pharmacological effects of the main groups of drugs that are commonly abused.
5	To describe some of the central issues involved in the development of new and improved drugs.

University Graduate Attributes

This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:

University Graduate Attribute	Course Learning Outcome(s)
Knowledge and understanding of the content and techniques of a chosen discipline at advanced levels that are internationally recognised.	1-4
The ability to locate, analyse, evaluate and synthesise information from a wide variety of sources in a planned and timely manner.	1-3, 5
An ability to apply effective, creative and innovative solutions, both independently and cooperatively, to current and future problems.	2-5
A commitment to continuous learning and the capacity to maintain intellectual curiosity throughout life.	1-4
An awareness of ethical, social and cultural issues within a global context and their importance in the exercise of professional skills and responsibilities.	4, 5

Learning Resources

Required Resources

“Rang and Dale's pharmacology” by Rang, Dale, Ritter,
Flower and Henderson (Elsevier, 2012, 7th Edition). This book is an excellent introduction to all
aspects of pharmacology and lecturers will assign relevant chapters for each lecture.

The prescribed texts are integral to the course and may be purchased from:
Unibooks, 成人大片
ADELAIDE SA 5005
Website www.unibooks.com.au

Recommended Resources

Lecture handouts and recordings will be available through MyUni. Tutorial responses will also be through MyUni and the small group workshops will produce a wiki as part of the workshop.

Learning & Teaching Modes

Pharma-CAL-ogy” Packages - Computer Assisted Instruction
“Pharma-CAL-ogy” Packages are computer-based learning software packages that are interactive and can be used to support lecture materials and simulations of pharmacological preparations. Students who used these packages found them an extremely valuable resource for learning the principles of Pharmacology. “Pharma-CAL-ogy” packages can be accessed through the Faculty of Health Sciences computers located at Barr Smith South Building.

ACADEMIC LEARNING & LANGUAGE (ALL)

* - Level 3 East,
Undergraduate students can access individualised help in the Writing Centre. There are also academic writing and skills development seminars held each semester, as well as a range of online resources available from ‘Writing and Speaking at Uni’ through MyUni, and the ALL printed learning guides;

MATHS LEARNING SERVICE (MLS)

The Service offers free support for all 成人大片 students meeting maths (including stats) in their studies, especially for the first time. We offer the following services:

No appointment is necessary. Check the website for opening hours during the breaks.

Bridging Courses
The MLS provides self-paced bridging courses to cover prerequisite maths knowledge.

For further information:
Maths Learning Centre

Level 3 East, Hub Central
THE UNIVERSITY OF ADELAIDE
SA 5005
AUSTRALIA
Email

Workload

The information below is provided as a guide to assist students in engaging appropriately with the course requirements.

The information below is provided as a guide to assist students in engaging appropriately with the course requirements.

You should spend at minimum 12 hours a week on study activities for this course.
This will include an average of 4 hours contact time (lecture/workshop/tutorial) and 8 hours
revision/preparation/study.

Learning Activities Summary

Week	Topic	Lecture
Week 1	Intro to Pharmacology	Targets of Drug Action
Week 2	Intro to Pharmacology	Pharmacodynamic Concepts
Week 3	Intro to Pharmacology Autonomic Pharmacology	Pharmacokinetic Concepts Overview of the ANS
Week 4	Autonomic Pharmacology	Cholinergic Drugs Adrenergic Drugs
Week 5	Applied Pharmacology	Drugs & Inflammation Drugs & the GI-Tract
Week 6	Applied Pharmacology	Drugs & Asthma Drugs & Bacteria
Week 7	Applied Pharmacology	Drugs & Viruses
Week 8	Applied Pharmacology CNS Pharmacology	Drugs & Cancer Overview of the CNS
Week 9	CNS Pharmacology	Drugs of Dependence CNS stimulants
Week 10	CNS Pharmacology	Drugs & Pain Control Drugs & Mental Disorders
Week 11	Modern Issues in Pharmacology	Making Better Drugs Natural Vs Synthetic Drugs
Week 12	Complementary Therapies Exam Information Session & Pharm III Overview	Complementary Therapies Exam Information Session & Pharm III Overview

The University's policy on Assessment for Coursework Programs is based on the following four principles:

Assessment must encourage and reinforce learning.
Assessment must enable robust and fair judgements about student performance.
Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
Assessment must maintain academic standards.

Assessment Summary

Assessment Task	Assessment Type	Weighting	Learning Outcome(s) being addressed
Final Exam	Summative	60%	1-5
Mid Semester Test	Summative	15%	1-5
Drug Profile Assignment	Summative	15%	1-5
Online Workshops	Summative	10%	1-3

Assessment Detail

1. Final Exam
A 3 hour written paper held during exam week at the end of semester comprises 60% of your final grade. The exam will assess material from the whole of the lecture course, using a combination of multiple choice, short answer and essay questions.

2. Mid Semester test
This test will be based on lecture material from week 1 till end of week 5 and will comprise 15% of the final grade. The test will employ multiple choice questions and will be held during week seven.

3. Drug Profile Assignment
Studying the properties of individual drugs enhances the learning of pharmacological principles, since concepts covered in lectures often make more sense after seeing them exemplified in specific drugs. This exercise requires you to conduct library-based research into a widely used drug in order to gain an appreciation for its properties including:
i. Basic Pharmacodynamics Properties of the assigned drug
ii. Basic Pharmacokinetic Properties of the assigned drug
iii. Therapeutic Applications of the assigned drug
iv. Major Contraindications and adverse side effects of the assigned drug
The Drug profile assignment will comprise 15% of your final grade. Each student will be assigned a drug and required to complete an online assignment. Detailed information about the assignment will be posted on MyUni.

4. Online Workshops
This will comprise 10% of the final grade. Some of the tutorial sessions will be used to introduce the content of the workshop material. The workshops material will be assessed via online assignments and must be completed by the “Due Date”. Detailed information about the online workshops will be posted on MyUni,
i. Getting the Dose Right
This Workshop will introduce you to the basic skills needed when calculating, preparing and administering drug doses. These skills are vitally important in any area of drug-based research.
ii. Intro to Organ Bath
This workshop introduces you to the use of an organ bath during the study of the effects of drugs within isolated animal tissues. Involves the use of an organ bath simulation package entitled “Simulations of Experiments on Isolated Guinea Pig Ileum.”
iii. Agonist/Antagonist Drugs
This workshop introduces you to the way in which the effects of different types of drugs (e.g. agonists, antagonists) can be distinguished and characterised using an organ bath-based experimental approach. Involves the use of an organ bath simulation package entitled “Simulations of Experiments on Isolated Guinea Pig Ileum.”
iv. Statistical Analysis
In this workshop we will explore how we describe data in statistics, how we test hypotheses in statistics and how to choose an appropriate test.

Submission

All submissions are electronic via MyUni.
Late submissions of any student work are not acceptable. Coursework received after the deadline will be penalised as follows:
15% of total available points will be penalised per day (24 hour period or fraction
thereof).
An automatic zero mark will be applied after 7 days. For example, coursework submitted any time after the deadline up to 24 hours late and marked as a 75% would become 60% (i.e. a 15% penalty). A 55% grade would become a 40%.Coursework submitted to any location other than those specified will not be accepted. This includes submissions to personal staff email addresses. Weekends and public holidays ARE included as penalty days. Extensions will only be granted in exceptional circumstances following the provision of supporting documentation (e.g. a medical certificate) to the course coordinator BEFORE the due date and time of submission.

Course Grading

Grades for your performance in this course will be awarded in accordance with the following scheme:

M10 (Coursework Mark Scheme)
Grade	Mark	Description
FNS		Fail No Submission
F	1-49	Fail
P	50-64	Pass
C	65-74	Credit
D	75-84	Distinction
HD	85-100	High Distinction
CN		Continuing
NFE		No Formal Examination
RP		Result Pending

Further details of the grades/results can be obtained from Examinations.

Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.

Final results for this course will be made available through .

Replacement Assessment
Academic replacement assessments will be offered at the discretion of the School and only to students whose overall marks are within 5% of a Pass grade (i.e. 45%). If students feel their exam performance was impeded by medical or personal factors, applications for replacement assessments on Medical or Compassionate grounds may be made. Note that colds and minor
respiratory infections do not constitute grounds for granting replacement examinations. Students should make every reasonable attempt to sit the final exam, and must apply for replacement assessments. Replacement assessment application forms and forms for completion by Medical Practitioners are available at: http://www.adelaide.edu.au/student/current/exams/ .

Student Feedback

The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.

SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.
Student Support
Policies & Guidelines
This section contains links to relevant assessment-related policies and guidelines - all university policies.
Fraud Awareness

Students are reminded that in order to maintain the academic integrity of all programs and courses, the university has a zero-tolerance approach to students offering money or significant value goods or services to any staff member who is involved in their teaching or assessment. Students offering lecturers or tutors or professional staff anything more than a small token of appreciation is totally unacceptable, in any circumstances. Staff members are obliged to report all such incidents to their supervisor/manager, who will refer them for action under the university's student鈥檚 disciplinary procedures.

The 成人大片 is committed to regular reviews of the courses and programs it offers to students. The 成人大片 therefore reserves the right to discontinue or vary programs and courses without notice. Please read the important information contained in the disclaimer.

Authorised by:	Deputy Vice-Chancellor and Vice-President (Academic)
Maintained by:	Course Outlines Administrator

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