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1. describe the underlying principles of chemical equilibrium, thermodynamics and kinetics in the context of biological systems, and be able to clearly communicate the link between these quantitative means of characterising biochemical reactions;
2. describe the underlying principles of medicinal chemistry;
3. develop syntheses of relevant medicinal agents;
4. describe the chemistry of metalloenzymes and metalloproteins;
5. provide a broad description of biologically important molecules and have a firm understanding of the chemistry and reactivity of these molecules;
6. design, conduct, analyse and interpret results of an experiment, and effectively communicate these in written reports

Biophysical Chemistry: ‘Physical Chemistry for the Biosciences’, (Chang, 1st Edition, University Science Books, 2005) ISBN: 1891389335

Bioinorganic Chemistry: ‘Inorganic Chemistry’ (Shriver & Atkins, 3rd Edition, Oxford University Press, 1999) - later edition available as well

Medicinal Chemistry: ‘An Introduction to Medicinal Chemistry’ (G. L. Patrick: 3rd Edition, Oxford University Press, 2005)

Bioorganic Chemistry: To be announced.

MyUni: Teaching materials and course documentation will be posted on the MyUni website ().

Maths Resources 
The Maths Learning Centre (MLC) helps all students learn and use the maths they need at uni. The MLC offers seminars, workshops, online, and print resources.  It also run a drop-in room in Hub Central from 10am to 4pm Monday to Friday during teaching weeks.

For more information, visit

For chemistry-specific maths help, visit
 

Lectures 36 x 50-minute sessions with three sessions per week

Tutorials 11 x 50-minute sessions with one session per week

Practicals 8 x 5-hour sessions

A student enrolled in a 3 unit course, such as this, should expect to spend, on average 12 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).

The course content includes the following:

Bio-thermodynamics and Enzyme Kinetics.
Role of thermodynamics and kinetics with specific applications in drug binding, dialysis and osmosis.

Metalloproteins and Enzymes
An introduction to the arena of biomimetic inorganic chemistry will be presented, including extensive discussion of the structure and function of metalloenzymes. This section will emphasise how the principles of nature can be applied to the rational design of metallic species capable of controlled nitrogen, carbon dioxide, carbon monoxide and methane activation.

Principles of Medicinal Chemistry
An introduction to the principles of medicinal chemistry including synthesis, natural product isolation, lead generation, lead optimisation and quantitative structure-activity relationships will be presented. The principles of parallel and combinatorial synthesis will be presented in this context.

Natural Products and Bio-Polymers
DNA/RNA, terpenes and alkaloids. Concept of natural molecules as targets and leads. Introduction to the biosynthesis of these compounds.

Practicals
There will be 8 sessions from Weeks 2 – 11. The practical exercises will provide students with "hands on" experience in the synthesis and analysis of molecules of medicinal and biological relevance.

Some students repeating the course may be exempted from practical classes. Please note that exemptions will only be granted to students who attempted and achieved an overall practical mark of at least 50% in the course in the previous year. Applications for exemption should be lodged with the School of Physical Sciences office.

Tutorials
Tutorials will be used to reinforce the concepts introduced in lectures.

Attendance is compulsory at all scheduled chemistry practical sessions.

Assessment task	Type of assessment	Percentage of total assessment for grading purposes	Hurdle (Yes/No)	Outcomes being assessed
Assignments	Summative	10%	No	1 – 6
Extended Practical Report	Summative	5%	No	6
Practical Reports	Formative & Summative	25%	Yes (50%)	1 – 6
Exam	Summative	60%	Yes (45%)	1 – 6

Practical work is compulsory – This includes conduct of required experimental work, attendance at demonstrator interviews (as required) and submission of the laboratory reports.

To pass this course students must:

• Attain a minimum of 45% for the exam:
• Students who attain a final course grade of at least 45% but do not attain a minimum of 45% for the exam may be offered an Additional Academic Exam during the Replacement/Additional Assessment period, in line with the Modified Arrangements for Coursework Assessment Policy.

Assignments (10%)
There will be 4 assignments, each worth 2.5%. Each assignment will consist of a series of short-answer and/or multiple-choice questions. Students will submit the assignments electronically.

Practical Reports (30%)
Students will complete 8 practicals and submit a short report for each practical. Each short report will contribute 3.75% towards the final grade. These reports are important in assessing the students' understanding of the practical and their competency in the skills involved in each practical.

Final exam (60%)
The end-of-semester examination will be based primarily on lecture/tutorial material and will consist of a series of short-answer and/or multiple-choice questions.

 

Submission of Assigned Work
Coversheets must be completed and attached to all submitted work. Instructions on how to submit your work and coversheets will be provide on MyUni.

Extensions for Assessment Tasks
Extensions of deadlines for assessment tasks may be allowed for reasonable causes. Such situations would include compassionate and medical grounds of the severity that would justify the awarding of a supplementary examination. Evidence for the grounds must be provided when an extension is requested. Students are required to apply for an extension to the Course Coordinator before the assessment task is due. Extensions will not be provided on the grounds of poor prioritising of time. 

Late submission of assessments
If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days or more late without an approved extension can only receive a maximum of 50% of the mark.