CHEM 3213 - Advanced Synthetic Methods III

North Terrace Campus - Semester 2 - 2021

Theoretical aspects and applications of a variety of synthetically useful reactions are presented. The course continually expands the arsenal of powerful synthetic methods available and exemplifies their uses. It focuses on efficiency (how is the greatest amount of the desired compound obtained in the fewest steps?), chemo- and regio-selectivity (how is the desired reaction obtained only at the site of interest?) and stereochemistry (how are the absolute and relative stereochemistry of the products of various reactions controlled?). An overview is given of synthetic strategy including the design and control of stereochemistry in the synthesis of complex molecules. The applications of chemical principles in a variety of contexts including industrial processes & chiral synthesis are addressed.

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Course Details

Course Code	CHEM 3213
Course	Advanced Synthetic Methods III
Coordinating Unit	School of Physical Sciences
Term	Semester 2
Level	Undergraduate
Location/s	North Terrace Campus
Units	3
Contact	Up to 9 hours per week
Available for Study Abroad and Exchange	Y
Prerequisites	CHEM 2545, CHEM 2550
Assumed Knowledge	CHEM 3610, CHEM 3620
Assessment	Exam, practical work, assignments

Course Staff

Course Coordinator: Associate Professor David Huang

Course Timetable

The full timetable of all activities for this course can be accessed from .

Course Learning Outcomes

On successful completion of this course, students will be able to:

1	describe and explain the use of the carbonyl group, stereoselectivity, and organometallic reagents and catalysts in chemical synthesis.
2	propose mechanisms for chemical reactions, given starting materials, reagents, conditions, and/or products.
3	explain the role and relevance of organic synthesis and organometallic reagents and catalysts in industrial processes.
4	demonstrate proficiency in undertaking individual and/or team-based laboratory investigations using appropriate apparatus and safe laboratory practices.
5	collect, record, analyse and interpret results of an experiment, and effectively communicate these results in written reports.
6	design and plan an investigation by selecting and applying appropriate practical and/or theoretical techniques or tools.

University Graduate Attributes

This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:

University Graduate Attribute	Course Learning Outcome(s)
Deep discipline knowledge informed and infused by cutting edge research, scaffolded throughout their program of studies acquired from personal interaction with research active educators, from year 1 accredited or validated against national or international standards (for relevant programs)	1-6
Critical thinking and problem solving steeped in research methods and rigor based on empirical evidence and the scientific approach to knowledge development demonstrated through appropriate and relevant assessment	1,2,5,6
Teamwork and communication skills developed from, with, and via the SGDE honed through assessment and practice throughout the program of studies encouraged and valued in all aspects of learning	4,5
Career and leadership readiness technology savvy professional and, where relevant, fully accredited forward thinking and well informed tested and validated by work based experiences	1-6
Intercultural and ethical competency adept at operating in other cultures comfortable with different nationalities and social contexts able to determine and contribute to desirable social outcomes demonstrated by study abroad or with an understanding of indigenous knowledges	3-6
Self-awareness and emotional intelligence a capacity for self-reflection and a willingness to engage in self-appraisal open to objective and constructive feedback from supervisors and peers able to negotiate difficult social situations, defuse conflict and engage positively in purposeful debate	4-6

Learning Resources
Required Resources

There is no prescribed text for this course. All required course material will be provided by the course instructor(s).

Recommended Resources
Textbooks
- Clayden, Greeves, and Warren, Organic Chemistry (Oxford University Press)
- Silverstein, Webster, Kiemle, and Bryce, Spectroscopic Identification of Organic Compounds (Wiley)
All of these texts are available for loan from the Barr Smith library. References to other material and recent literature will be given in
lectures.
Online Learning

Teaching materials and course documentation will be posted on the MyUni website ().
Learning & Teaching Activities
Learning & Teaching Modes
This course consists of the following components:
- Lectures/Tutorials: 12 x 3 hours per week (timetabled as "Workshops")
- Practicals: 10 x 5.5-hour sessions with one session per week
Workload

The information below is provided as a guide to assist students in engaging appropriately with the course requirements.

A student enrolled in a 3 unit course, such as this, should expect to spend, on average 12 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).

Learning Activities Summary
Coursework
Course material will cover the following topics:
- Metals in Synthesis
- Saturated Heterocycles & Carbocycles
- Stereoselective Synthesis
Practicals
Practical exercises will provide students with "hands on" experience in the design and conduct of contemporary synthetic chemistry experiments. These skills-based sessions will allow students to develop their control of chemical reactivity, synthesise and isolate molecular targets, and characterise the structure and properties, all in a safe manner. Training and direction on communicating the results of these investigations in various formats will be provided.

Tutorials
Tutorial sessions will be held weekly and will provide the student with the opportunity to discuss material from the lecture course. Formative tutorial questions will be used to reinforce the concepts introduced in lectures through a combination of qualitative and quantitative problem solving.
Specific Course Requirements

Attendance is compulsory at all scheduled chemistry practical sessions. The learning outcomes for this course are substantially dependent on laboratory experience and practice. Therefore, missing any practical class in a semester will result in a grade of FAIL being recorded for the course. Students with medical or compassionate reasons for non-attendance will be given an opportunity to make up missed practical sessions.

The University's policy on Assessment for Coursework Programs is based on the following four principles:

Assessment must encourage and reinforce learning.
Assessment must enable robust and fair judgements about student performance.
Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
Assessment must maintain academic standards.

Assessment Summary

Assessment task	Type of assessment	Percentage of total assessment for grading purposes	Hurdle (Yes/No)	Outcomes being assessed	Approx timing of Assessment
Summative Assignments	Formative & Summative	10%	No	1-4	Weeks 5,9,13
Practical	Formative & Summative	30%	No	1–6	Bi-weekly, major reports due every 3 weeks
Exam	Summative	60%	Yes (45%)	1–4	Examination period

Assessment Related Requirements

Assessment Item	% needed to meet course requirement	Additional Assessment
Examination	45%	Yes - RAA Exam; a grade of at least 45% must obtained
Practical work is compulsory	Satisfactory completion of all practicals, including attendance of ALL practical sessions and reasonable attempt at ALL practical reports	Missed practicals can be made up

Assessment Detail

Summative Assignments (10% of final course grade)
Students will complete assignments on the course material. There will be 3 assignments each worth 3.33%. The topics are Metals in Synthesis, Saturated Heterocycles & Carbocycles, and Stereoselective Synthesis. Each assignment will consist of a series of short-answer and/or multiple-choice questions.

Practical (30% of final course grade)
This will come from assessment of experiment reports (3 major reports and 2 minor reports) and in-lab assessments. Each major report is worth 6% of the assessment, each minor report is worth 3% of the assessment, and each in-lab assessment is worth 2% of the assessment. Students will be provided with sample reports, rubrics with assessment criteria, and guidelines on report structure and approximate length. Students will complete 5 experiments, with each experiment taking approximately 2 lab sessions (1 experiment approximately every 2 weeks). They will submit a minor report on the day of completion of an experiment for 2 of the 5 experiments and they will complete an in-lab assessment and submit a major report approximately one week after the completion of an experiment for the other 3 experiments. The in-lab assessment will assess risk assessment, experimental write-up, successful synthesis, and laboratory skills.

Examination (60% of final course grade)
The end-of-semester examination will be based primarily on lecture/tutorial material and will consist of a series of short-answer and/or multiple-choice questions.

Submission

Submission of Assigned Work
Coversheets must be completed and attached to all submitted work. Coversheets can be obtained from the School Office (room G33 Physics) or from MyUNI. Work should be submitted via the assignment drop box at the School Office or via MyUni as instructed.

Extensions for Assessment Tasks
Extensions of deadlines for assessment tasks may be allowed for reasonable causes. Such situations would include compassionate and medical grounds of the severity that would justify the awarding of a supplementary examination. Evidence for the grounds must be provided when an extension is requested. Students are required to apply for an extension to the Course Coordinator before the assessment task is due. Extensions will not be provided on the grounds of poor prioritising of time. The assessment extension application form can be obtained from:

Late Submission of Assessments
If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days or more late without an approved extension can only receive a maximum of 50% of the mark.

Course Grading

Grades for your performance in this course will be awarded in accordance with the following scheme:

M10 (Coursework Mark Scheme)
Grade	Mark	Description
FNS		Fail No Submission
F	1-49	Fail
P	50-64	Pass
C	65-74	Credit
D	75-84	Distinction
HD	85-100	High Distinction
CN		Continuing
NFE		No Formal Examination
RP		Result Pending

Further details of the grades/results can be obtained from Examinations.

Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.

Final results for this course will be made available through .

Student Feedback

The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.

SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.
Student Support
Policies & Guidelines
This section contains links to relevant assessment-related policies and guidelines - all university policies.
Fraud Awareness

Students are reminded that in order to maintain the academic integrity of all programs and courses, the university has a zero-tolerance approach to students offering money or significant value goods or services to any staff member who is involved in their teaching or assessment. Students offering lecturers or tutors or professional staff anything more than a small token of appreciation is totally unacceptable, in any circumstances. Staff members are obliged to report all such incidents to their supervisor/manager, who will refer them for action under the university's student鈥檚 disciplinary procedures.

The 成人大片 is committed to regular reviews of the courses and programs it offers to students. The 成人大片 therefore reserves the right to discontinue or vary programs and courses without notice. Please read the important information contained in the disclaimer.

Authorised by:	Deputy Vice-Chancellor and Vice-President (Academic)
Maintained by:	Course Outlines Administrator

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